Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Chaganti Raju S.K.
 2. Date of Event Requiring Statement (Month/Day/Year)
04/04/2013		 3. Issuer Name and Ticker or Trading Symbol
CANCER GENETICS, INC [CGIX]
(Last)
(First)
(Middle)
201 ROUTE 17 NORTH, 2ND FLOOR		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

RUTHERFORD, NJ 07070		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock, par value $0.0001 per share 183,977
D
 
Common Stock, par value $0.0001 per share 60,000
I
By limited liability company
Common Stock, par value $0.0001 per share 97,826
I
By spouse
Common Stock, par value $0.0001 per share 30,000
I
By Seeta R. Chaganti 2011 Grantor Retained Annuity Trust#1
Common Stock, par value $0.0001 per share 33,494
I
By Seeta R. Chaganti 2011 Grantor Retained Annuity Trust#2
Common Stock, par value $0.0001 per share 20,000
I
By Raju Chaganti 2011 Grantor Retained Annuity Trust

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy)   (1) 03/31/2019 Common Stock, par value $0.0001 per share 100,000 $ 4 D  
Stock Option (right to buy)   (2) 09/14/2020 Common Stock, par value $0.0001 per share 36,000 $ (2) D  
Convertible Note   (3)   (3) Common Stock, par value $0.0001 per share (3) $ (3) D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Chaganti Raju S.K.
201 ROUTE 17 NORTH
2ND FLOOR
RUTHERFORD, NJ 07070		   X      

Signatures

/s/ Raju S.K. Chaganti 04/04/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) This option was fully vested and exercisable on April 1, 2009.
(2) This option is currently vested and exercisable as to 30,000 shares. The remaining shares will vest and become exercisable in equal quarterly installments. The exercise price will be equal to the initial public offering price.
(3) The reporting person agreed to convert $100,000 of the outstanding principal balance under the note plus all accrued and unpaid interest thereon into shares of common stock of Cancer Genetics, Inc. (the "Company") upon consummation of the Company's initial public offering at a conversion price equal to the initial public offering price.

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