UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Bristol-Myers Squibb Company (Name of Issuer) Common Stock (Title of Class of Securities) 110122108 (CUSIP Number) April 28, 2006 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [X] Rule 13d-1(b) [ ] Rule 13d-1(c) [ ] Rule 13d-1(d) *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). CUSIP: 110122108 Page 1 of 6 1 NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY) Capital Research and Management Company 95-1411037 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS) (a) (b) 3 SEC USE ONLY 4 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware 5 SOLE VOTING POWER 56,896,200 6 SHARED VOTING POWER NUMBER OF SHARES NONE BENEFICIALL Y OWNED BY 7 SOLE DISPOSITIVE POWER EACH REPORTING 201,935,900 PERSON WITH: 8 SHARED DISPOSITIVE POWER NONE 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 201,935,900 Beneficial ownership disclaimed pursuant to Rule 13d- 4 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS) 11 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9 10.3% 12 TYPE OF REPORTING PERSON (SEE INSTRUCTIONS) IA CUSIP: 110122108 Page 2 of 6 SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 Schedule 13G Under the Securities Exchange Act of 1934 Amendment No. 3 Item 1(a) Name of Issuer: Bristol-Myers Squibb Company Item 1(b) Address of Issuer's Principal Executive Offices: 345 Park Avenue New York, NY 10154 Item 2(a) Name of Person(s) Filing: Capital Research and Management Company Item 2(b) Address of Principal Business Office or, if none, Residence: 333 South Hope Street Los Angeles, CA 90071 Item 2(c) Citizenship: N/A Item 2(d) Title of Class of Securities: Common Stock Item 2(e) CUSIP Number: 110122108 Item 3 If this statement is filed pursuant to sections 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a: (d) [X] Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8). (e) [X] An investment adviser in accordance with section 240.13d-1(b)(1)(ii)(E). Item 4 Ownership Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. See page 2 (a) Amount beneficially owned: (b) Percent of class: (c) Number of shares as to which the person has: (i) Sole power to vote or to direct the vote: (ii) Shared power to vote or to direct the vote: (iii) Sole power to dispose or to direct the disposition of: (iv) Shared power to dispose or to direct the disposition of: CUSIP: 110122108 Page 3 of 6 Capital Research and Management Company, an investment adviser registered under Section 203 of the Investment Advisers Act of 1940 is deemed to be the beneficial owner of 201,935,900 shares or 10.3% of the 1,956,521,000 shares of Common Stock believed to be outstanding as a result of acting as investment adviser to various investment companies registered under Section 8 of the Investment Company Act of 1940. Item 5 Ownership of Five Percent or Less of a Class. If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following: [ ] Item 6 Ownership of More than Five Percent on Behalf of Another Person: N/A Item 7 Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.: N/A Item 8 Identification and Classification of Members of the Group: N/A Item 9 Notice of Dissolution of Group: N/A Item 10 Certification By signing below, I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect. Signature After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Date: May 10, 2006 Signature: *Paul G. Haaga, Jr. Name/Title: Paul G. Haaga, Jr., Executive Vice President Capital Research and Management Company *By /s/ James P. Ryan James P. Ryan Attorney-in-fact Signed pursuant to a Power of Attorney dated March 9, 2006 included as an Exhibit to this Schedule 13G. CUSIP: 110122108 Page 4 of 6 Power of Attorney The Undersigned do hereby appoint James P. Ryan, Liliane Corzo and Angela Mitchell, and each of them, acting singly, with full power of substitution, as the true and lawful attorney of the undersigned, to sign on behalf of the undersigned in respect of the ownership of equity securities deemed held by the undersigned, Capital Research and Management Company, AMCAP Fund, Inc., American Balanced Fund, Inc., American High-Income Trust, American Mutual Fund, Inc., American Funds Insurance Series (Growth Fund, International Fund, Grow-Income Fund, Asset Allocation Fund, Global Growth Fund, Global Small Capitalization Fund, New World Fund), The Bond Fund of America, Inc., Capital Income Builders, Inc., Capital World Growth and Income Fund, Inc., EuroPacific Growth Fund, Inc., Fundamental Investors, Inc., The Growth Fund of American, Inc., The Income Fund of American, Inc., The Investment Company of America, Inc., The New Economy Fund, New Perspective Fund, Inc., New World Fund, Inc., SMALLCAP World Fund, Inc., and Washington Mutual Investors Fund, Inc., IN WITNESS WHEREOF, this Power of Attorney, has been executed as th of the 9 day of March, 2006. Capital Research and Management Company /s/ Paul G. Haaga, Jr. ----------------------------------------------------- Name: Paul G. Haaga, Jr. Title: Executive Vice President American Balanced Fund, Inc. The Growth Fund of America, Inc. The Income Fund of America, Inc. Fundamental Investors, Inc. /s/ Patrick F. Quan ----------------------------------------------------- Name: Patrick F. Quan Title: Secretary American High-Income Trust Bond Fund of America, Inc. /s/ Kimberly S. Verdick ----------------------------------------------------- Name: Kimberly S. Verdick Title: Secretary American Funds Insurance Series The New Economy Fund SMALLCAP World Fund, Inc. /s/ Chad L. Norton ----------------------------------------------------- Name: Chad L. Norton Title: Secretary AMCAP Fund, Inc. CUSIP: 110122108 Page 5 of 6 American Mutual Fund, Inc. Capital Income Builder, Inc. Capital World Growth and Income Fund, Inc. Europacific Growth Fund The Investment Company of America New Perspective Fund, Inc. New World Fund, Inc. /s/ Vincent P. Corti ----------------------------------------------------- Name: Vincent P. Corti Title: Secretary Washington Mutual Investors Fund, Inc. /s/ Michael W. Stockton ----------------------------------------------------- Name: Michael W. Stockton Title: Vice President, Assistant Secretary and Treasurer CUSIP: 110122108 Page 6 of 6