UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                  SCHEDULE 13G


                   Under the Securities Exchange Act of 1934
                               (Amendment No. 1)*


                           INTERPHARM HOLDINGS, INC.
                                (Name of Issuer)


                    COMMON STOCK, PAR VALUE $0.01 PER SHARE
                         (Title of Class of Securities)


                                   460588106
                                 (CUSIP Number)

                               DECEMBER 31, 2006
            (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

             [_]  Rule 13d-1(b)
             [X]  Rule 13d-1(c)
             [_]  Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting  person's
initial  filing on this form with respect to the subject  class of  securities,
and for any  subsequent  amendment  containing  information  which  would alter
disclosures provided in a prior cover page.

The information required on the reminder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).


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CUSIP NO. 460588106               Schedule 13G                     Page 2 of 12
---------------------                                         ------------------

--------------------------------------------------------------------------------
1.   Name of Reporting Person:          Aisling Capital II, LP
     S.S. or I.R.S. Identifica-
     tion No. of Above Person

--------------------------------------------------------------------------------
2.   Check the Appropriate Box                                       (a)  [_]
     if a Member of a Group                                          (b)  [X]

--------------------------------------------------------------------------------
3.  SEC Use Only

--------------------------------------------------------------------------------
4.   Citizenship or Place of Organization      Delaware

--------------------------------------------------------------------------------
           Number of            5.  Sole Voting Power:         7,218,150*
            Shares              ------------------------------------------------
         Beneficially           6.  Shared Voting Power:       -0-
           Owned By             ------------------------------------------------
            Each                7.  Sole Dispositive Power:    7,218,150*
          Reporting             ------------------------------------------------
           Person               8.  Shared Dispositive Power:  -0-
--------------------------------------------------------------------------------
9.   Aggregate Amount Beneficially Owned by Each Reporting Person

     7,218,150*
--------------------------------------------------------------------------------
10.  Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares

                                                                          [_]
--------------------------------------------------------------------------------
11.  Percent of Class Represented by Amount in Row (9)         9.9%*

--------------------------------------------------------------------------------
12.  Type of Reporting Person                                  PN
--------------------------------------------------------------------------------

--------------------

*     This amount is an approximation,  which includes 122,241 shares of common
stock,  2,281,914 shares of common stock issuable upon the exercise of warrants
and  approximately  4,813,995  shares of common stock issuable upon the initial
conversion  of 10,000  shares of Series C-1  Convertible  Preferred  Stock (the
"Preferred Shares"). See Item 4(a).


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CUSIP NO. 460588106               Schedule 13G                     Page 3 of 12
---------------------                                         ------------------

--------------------------------------------------------------------------------
1.   Name of Reporting Person:          Aisling Capital Partners, LP
     S.S. or I.R.S. Identifica-
     tion No. of Above Person

--------------------------------------------------------------------------------
2.   Check the Appropriate Box                                       (a)  [_]
     if a Member of a Group                                          (b)  [X]

--------------------------------------------------------------------------------
3.  SEC Use Only

--------------------------------------------------------------------------------
4.   Citizenship or Place of Organization      Delaware

--------------------------------------------------------------------------------
           Number of            5.  Sole Voting Power:         7,218,150*
            Shares              ------------------------------------------------
         Beneficially           6.  Shared Voting Power:       -0-
           Owned By             ------------------------------------------------
            Each                7.  Sole Dispositive Power:    7,218,150*
          Reporting             ------------------------------------------------
           Person               8.  Shared Dispositive Power:  -0-
--------------------------------------------------------------------------------
9.   Aggregate Amount Beneficially Owned by Each Reporting Person

     7,218,150*
--------------------------------------------------------------------------------
10.  Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares

                                                                          [_]
--------------------------------------------------------------------------------
11.  Percent of Class Represented by Amount in Row (9)         9.9%

--------------------------------------------------------------------------------
12.  Type of Reporting Person                                  PN
--------------------------------------------------------------------------------

--------------------

*     This amount is an approximation,  which includes 122,241 shares of common
stock,  2,281,914 shares of common stock issuable upon the exercise of warrants
and  approximately  4,813,995  shares of common stock issuable upon the initial
conversion of the Preferred Shares. See Item 4(a).


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CUSIP NO. 460588106               Schedule 13G                     Page 4 of 12
---------------------                                         ------------------

--------------------------------------------------------------------------------
1.   Name of Reporting Person:          Aisling Capital Partners LLC
     S.S. or I.R.S. Identifica-
     tion No. of Above Person

--------------------------------------------------------------------------------
2.   Check the Appropriate Box                                       (a)  [_]
     if a Member of a Group                                          (b)  [X]

--------------------------------------------------------------------------------
3.  SEC Use Only

--------------------------------------------------------------------------------
4.   Citizenship or Place of Organization      Delaware

--------------------------------------------------------------------------------
           Number of            5.  Sole Voting Power:         7,218,150*
            Shares              ------------------------------------------------
         Beneficially           6.  Shared Voting Power:       -0-
           Owned By             ------------------------------------------------
            Each                7.  Sole Dispositive Power:    7,218,150*
          Reporting             ------------------------------------------------
           Person               8.  Shared Dispositive Power:  -0-
--------------------------------------------------------------------------------
9.   Aggregate Amount Beneficially Owned by Each Reporting Person

     7,218,150*
--------------------------------------------------------------------------------
10.  Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares

                                                                          [_]
--------------------------------------------------------------------------------
11.  Percent of Class Represented by Amount in Row (9)         9.9%

--------------------------------------------------------------------------------
12.  Type of Reporting Person                                  OO
--------------------------------------------------------------------------------

--------------------
*     This amount is an approximation,  which includes 122,241 shares of common
stock,  2,281,914 shares of common stock issuable upon the exercise of warrants
and  approximately  4,813,995  shares of common stock issuable upon the initial
conversion of the Preferred Shares. See Item 4(a).


---------------------                                         ------------------
CUSIP NO. 460588106               Schedule 13G                     Page 5 of 12
---------------------                                         ------------------

--------------------------------------------------------------------------------
1.   Name of Reporting Person:          Steve Elms
     S.S. or I.R.S. Identifica-
     tion No. of Above Person

--------------------------------------------------------------------------------
2.   Check the Appropriate Box                                       (a)  [_]
     if a Member of a Group                                          (b)  [X]

--------------------------------------------------------------------------------
3.  SEC Use Only

--------------------------------------------------------------------------------
4.   Citizenship or Place of Organization      United States

--------------------------------------------------------------------------------
           Number of            5.  Sole Voting Power:         -0-
            Shares              ------------------------------------------------
         Beneficially           6.  Shared Voting Power:       7,218,150*
           Owned By             ------------------------------------------------
            Each                7.  Sole Dispositive Power:    -0-
          Reporting             ------------------------------------------------
           Person               8.  Shared Dispositive Power:  7,218,150*
--------------------------------------------------------------------------------
9.   Aggregate Amount Beneficially Owned by Each Reporting Person

     7,218,150*
--------------------------------------------------------------------------------
10.  Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares

                                                                          [_]
--------------------------------------------------------------------------------
11.  Percent of Class Represented by Amount in Row (9)         9.9%

--------------------------------------------------------------------------------
12.  Type of Reporting Person                                  IN
--------------------------------------------------------------------------------

--------------------
*     This amount is an approximation,  which includes 122,241 shares of common
stock,  2,281,914 shares of common stock issuable upon the exercise of warrants
and  approximately  4,813,995  shares of common stock issuable upon the initial
conversion of the Preferred Shares. See Item 4(a).


---------------------                                         ------------------
CUSIP NO. 460588106               Schedule 13G                     Page 6 of 12
---------------------                                         ------------------

--------------------------------------------------------------------------------
1.   Name of Reporting Person:          Dennis Purcell
     S.S. or I.R.S. Identifica-
     tion No. of Above Person

--------------------------------------------------------------------------------
2.   Check the Appropriate Box                                       (a)  [_]
     if a Member of a Group                                          (b)  [X]

--------------------------------------------------------------------------------
3.  SEC Use Only

--------------------------------------------------------------------------------
4.   Citizenship or Place of Organization      United States

--------------------------------------------------------------------------------
           Number of            5.  Sole Voting Power:         -0-
            Shares              ------------------------------------------------
         Beneficially           6.  Shared Voting Power:       7,218,150*
           Owned By             ------------------------------------------------
            Each                7.  Sole Dispositive Power:    -0-
          Reporting             ------------------------------------------------
           Person               8.  Shared Dispositive Power:  7,218,150*
--------------------------------------------------------------------------------
9.   Aggregate Amount Beneficially Owned by Each Reporting Person

     7,218,150*
--------------------------------------------------------------------------------
10.  Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares

                                                                          [_]
--------------------------------------------------------------------------------
11.  Percent of Class Represented by Amount in Row (9)         9.9%

--------------------------------------------------------------------------------
12.  Type of Reporting Person                                  IN
--------------------------------------------------------------------------------

--------------------
*     This amount is an approximation,  which includes 122,241 shares of common
stock,  2,281,914 shares of common stock issuable upon the exercise of warrants
and  approximately  4,813,995  shares of common stock issuable upon the initial
conversion of the Preferred Shares. See Item 4(a).


---------------------                                         ------------------
CUSIP NO. 460588106               Schedule 13G                     Page 7 of 12
---------------------                                         ------------------

--------------------------------------------------------------------------------
1.   Name of Reporting Person:          Andrew Schiff
     S.S. or I.R.S. Identifica-
     tion No. of Above Person

--------------------------------------------------------------------------------
2.   Check the Appropriate Box                                       (a)  [_]
     if a Member of a Group                                          (b)  [X]

--------------------------------------------------------------------------------
3.  SEC Use Only

--------------------------------------------------------------------------------
4.   Citizenship or Place of Organization      United States

--------------------------------------------------------------------------------
           Number of            5.  Sole Voting Power:         -0-
            Shares              ------------------------------------------------
         Beneficially           6.  Shared Voting Power:       7,218,150*
           Owned By             ------------------------------------------------
            Each                7.  Sole Dispositive Power:    -0-
          Reporting             ------------------------------------------------
           Person               8.  Shared Dispositive Power:  7,218,150*
--------------------------------------------------------------------------------
9.   Aggregate Amount Beneficially Owned by Each Reporting Person

     7,218,150*
--------------------------------------------------------------------------------
10.  Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares

                                                                          [_]
--------------------------------------------------------------------------------
11.  Percent of Class Represented by Amount in Row (9)         9.9%

--------------------------------------------------------------------------------
12.  Type of Reporting Person                                  IN
--------------------------------------------------------------------------------

--------------------
*     This amount is an approximation,  which includes 122,241 shares of common
stock,  2,281,914 shares of common stock issuable upon the exercise of warrants
and  approximately  4,813,995  shares of common stock issuable upon the initial
conversion of the Preferred Shares. See Item 4(a).


---------------------                                         ------------------
CUSIP NO. 460588106               Schedule 13G                     Page 8 of 12
---------------------                                         ------------------


              Pursuant  to Rule  13d-2(b)  of  Regulation  13D-G of the General
Rules and  Regulations  under  the  Securities  and  Exchange  Act of 1934,  as
amended,  the undersigned (the "Reporting Persons") hereby amend their Schedule
13G  Statement,  dated  September  11,  2006,  relating to the shares of common
stock, par value $.01 per share (the "Common Stock" or "Shares"), of Interpharm
Holdings, Inc. (the "Company").

Item 1.       No material change.

Item 2.       No material change.

Item 3.       No material change.

Item 4.       OWNERSHIP.

              (a)     AMOUNT BENEFICIALLY OWNED:

                      Each  of  the   Reporting   Persons   may  be  deemed  to
                      beneficially own an aggregate of approximately  7,218,150
                      Shares,  which includes 122,241 Shares,  2,281,914 Shares
                      issuable upon the exercise of warrants and  approximately
                      4,813,995 Shares issuable upon the initial  conversion of
                      the Preferred Shares.  The certificate of designations of
                      the Preferred  Shares  contains a blocker  provision (the
                      "Blocker") under which the holder of the Preferred Shares
                      does not have the right to convert the  Preferred  Shares
                      into  Shares to the  extent  that such  conversion  would
                      result in beneficial ownership by the holder of more than
                      9.99% of the  number  of Shares  outstanding  immediately
                      after giving  effect to such  conversion.  As a result of
                      the Blocker,  the Reporting  Persons are reporting herein
                      their  beneficial  ownership  of the Shares  representing
                      9.9% of the current  outstanding  Shares.  If the Blocker
                      were not in place,  as of the date hereof,  the Reporting
                      Persons  may be  deemed  to own an  additional  1,751,443
                      Shares issuable upon  conversion of the Preferred  Shares
                      held for the account of Aisling Capital II, L.P.

              (b)     PERCENTAGE OWNED:

                      Based  on  calculations  made  in  accordance  with  Rule
                      13d-3(d),  and there being 72,253,761 Shares  outstanding
                      as of November 6, 2006, each of the Reporting Persons may
                      be deemed to beneficially own  approximately  9.9% of the
                      outstanding Common Stock.

              (c)     NUMBER OF SHARES AS TO WHICH SUCH PERSON HAS:

                      (i)  Each  of  Aisling,   Aisling  Partners  and  Aisling
                      Partners  GP may be deemed  to have sole  power to direct
                      the  voting  and  disposition  of  the  7,218,150  Shares
                      beneficially owned by Aisling.

                      (ii) By virtue of the relationships between and among the
                      Reporting  Persons  as  described  in Item 2, each of the
                      Reporting Persons,  other than Aisling,  Aisling Partners


---------------------                                         ------------------
CUSIP NO. 460588106               Schedule 13G                     Page 9 of 12
---------------------                                         ------------------


                      and Aisling Partners GP, may be deemed to share the power
                      to direct  the voting and  disposition  of the  7,218,150
                      Shares beneficially owned by Aisling.

Item 5.       OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS

              No material change.

Item 6.       OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON

              No material change.

Item 7.       IDENTIFICATION  AND  CLASSIFICATION  OF SUBSIDIARY WHICH ACQUIRED
              THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY

              No material change.

Item 8.       IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP

              No material change.

Item 9.       NOTICE OF DISSOLUTION OF GROUP

              No material change.

Item 10.      CERTIFICATION

              (b)  The  following   certification  shall  be  included  if  the
              statement is filed pursuant to ss.240.13d-1(c):

              By signing  below we certify  that,  to the best of our knowledge
              and belief,  the  securities  referred to above were not acquired
              and are not  held  for the  purpose  of or  with  the  effect  of
              changing  or  influencing  the  control  of  the  issuer  of  the
              securities  and were not acquired and are not held in  connection
              with or as a participant in any  transaction  having that purpose
              or effect.

                  [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]




---------------------                                         ------------------
CUSIP NO. 460588106               Schedule 13G                    Page 10 of 12
---------------------                                         ------------------


                                   SIGNATURES

              After  reasonable  inquiry and to the best of our  knowledge  and
belief,  the  undersigned  certify  that  the  information  set  forth  in this
statement is true, complete and correct.

Dated as of February 13, 2007

                                        AISLING CAPITAL II, LP


                                        By:   Aisling Capital Partners, LP
                                              General Partner


                                        By:   Aisling Capital Partners LLC
                                              Managing Member


                                        By:   /s/ Dennis Purcell
                                              -------------------------------
                                              Name:  Dennis Purcell
                                              Title: Senior Managing Director


                                        AISLING CAPITAL PARTNERS, LP


                                        By:   Aisling Capital Partners LLC
                                              Managing Member


                                        By:   /s/ Dennis Purcell
                                              -------------------------------
                                              Name:  Dennis Purcell
                                              Title: Senior Managing Director


                                        AISLING CAPITAL PARTNERS LLC


                                        By:   /s/ Dennis Purcell
                                              -------------------------------
                                              Name:  Dennis Purcell
                                              Title: Senior Managing Director




---------------------                                         ------------------
CUSIP NO. 460588106               Schedule 13G                    Page 11 of 12
---------------------                                         ------------------




                                           /s/ Steve Elms
                                           ----------------------
                                           Steve Elms


                                           /s/ Dennis Purcell
                                           ----------------------
                                           Dennis Purcell


                                           /s/ Andrew Schiff
                                           ----------------------
                                           Andrew Schiff








---------------------                                         ------------------
CUSIP NO. 460588106               Schedule 13G                    Page 12 of 12
---------------------                                         ------------------


                                 EXHIBIT INDEX


Exhibit 1.        Joint Filing Agreement as required by Rule 13d-1(k)(1)  under
                  the Securities  Exchange Act of 1934, as amended  (previously
                  filed).