Longeveron (NASDAQ: LGVN), a clinical-stage, regenerative-medicine biotechnology company developing cellular therapies for rare, life-threatening and chronic aging-related conditions, is presenting results from its Clear Mind phase 2a clinical trial at the Alzheimer’s Association International Conference(R) (“AAIC”). The conference began on July 28, 2024, and runs through Aug. 1, 2024; the event is being held in person in Philadelphia as well as online. According to the announcement, a Featured Research Session oral presentation discussed findings that show Longeveron’s Lomecel-B improved cognitive function, quality of life and brain volume in the treatment of mild Alzheimer’s disease. The company also noted that the study met key objectives, including advancing data supporting favorable benefit/risk profile, supporting target engagement and providing additional support for the efficacy profile of Lomecel-B. In addition, Lomecel-B minimized the loss in brain volume in areas associated with Alzheimer’s disease. “As a medicinal signaling cell therapy that has multiple potential mechanisms of action to address inflammatory responses in the brain, Lomecel-B offers potential to address the underlying pathology of Alzheimer’s disease without the limitations of previous therapies,” said Longeveron CEO Wa’el Hashad in the press release. “We are very encouraged by the safety profile and efficacy evidence that support the differentiated therapeutic potential of Lomecel-B and lay the foundation for its future clinical development. We’re pleased to connect with the Alzheimer’s community at AAIC 2024 and contribute to the growing body of evidence that fuels the continued development of novel therapeutics for this devastating disease.”
To view the full press release, visit https://ibn.fm/PpvDr
About Longeveron Inc.
Longeveron is a clinical-stage, biotechnology company developing regenerative medicines to address unmet medical needs. The company’s lead investigational product is Lomecel-B(TM), an allogeneic medicinal signaling cell (“MSC”) therapy product isolated from the bone marrow of young, healthy adult donors. Lomecel-B(TM) has multiple potential mechanisms of action encompassing provascular, proregenerative, anti-inflammatory, and tissue repair and healing effects with broad potential applications across a spectrum of disease areas. Longeveron is currently pursuing three pipeline indications: hypoplastic left heart syndrome (“HLHS”), Alzheimer’s disease and Aging-Related Frailty. Lomecel-B development programs have received five separate and distinct FDA designations: for the HLHS program – Orphan Drug designation, Fast Track designation and Rare Pediatric Disease designation; and for the Alzheimer’s disease program – Regenerative Medicine Advanced Therapy (“RMAT”) designation and Fast Track designation. To learn more about the company, visit www.Longeveron.com.
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