Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
EVNIN LUKE
  2. Issuer Name and Ticker or Trading Symbol
Pharmasset Inc [VRUS]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
C/O MPM ASSET MANAGEMENT, 200 CLARENDON STREET, 54TH FLOOR
3. Date of Earliest Transaction (Month/Day/Year)
06/19/2008
(Street)

BOSTON, MA 02116
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 06/19/2008   S   153,700 (1) D $ 19.9 2,120,431 I See Footnote (2)
Common Stock 06/19/2008   S   500 (3) D $ 19.91 2,119,931 I See Footnote (4)
Common Stock 06/19/2008   S   100 (5) D $ 19.92 2,119,831 I See Footnote (6)
Common Stock 06/19/2008   S   100 (7) D $ 19.94 2,119,731 I See Footnote (8)
Common Stock 06/19/2008   S   1,400 (9) D $ 20 2,118,331 I See Footnote (10)
Common Stock               57,353 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
EVNIN LUKE
C/O MPM ASSET MANAGEMENT
200 CLARENDON STREET, 54TH FLOOR
BOSTON, MA 02116
    X    

Signatures

 /s/ Luke Evnin   06/23/2008
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These shares were sold as follows: 68,391 shares by BB BioVentures, L.P. ("BBBV"), 9,220 shares by MPM BioVentures Parallel Fund, L.P. ("BV PF"), 815 shares by MPM Asset Management Investors 1999 LLC ("AM 1999"), 3,971 shares by MPM BioVentures III, L.P., ("BV III"), 59,073 shares by MPM BioVentures III-QP, L.P. ("BV III QP"), 4,993 shares held by MPM BioVentures III GmbH & Co. Beteiligungs KG ("BV KG"), 1,785 shares by MPM BioVentures III Parallel Fund, L.P. ("BV III PF"), 1,403 shares held by MPM Asset Management Investors 2004 BVIII LLC ("AM BV III"), 3,949 by MPM BioVentures III GP, LP ("BV III GP") and 100 by MPM Capital, L.P. ("MPM LP"). MPM BioVentures I, L.P. ("BV I") and MPM BioVentures I LLC ("BV I LLC") are the direct and indirect general partners of BV PF. BAB BioVentures L.P. ("BAB BV"), BAB BioVentures, N.V. ("BAB NV") and BV I LLC are the direct and indirect general partners of BBBV. The Reporting Person is a manager of AM 1999 and BV I LLC. BV III GP and MPM BioVentures III LLC ("BV III LLC") are the direct and indirect general partners of BV III, BV III QP, BV III PF and BV KG. The Reporting Person is a Series A member of BV III LLC and a manager of AM BV III. The Reporting Person has a controlling interest in MPM LP. The Reporting Person disclaims beneficial ownership of all such shares except to the extent of his proportionate pecuniary interests therein.
(2) The shares are held as follows: 943,507 by BBBV, 127,194 by BV PF, 11,251 by AM 1999, 54,801 by BV III, 814,953 by BV III QP, 68,868 by BV KG, 24,612 by BV III PF, 19,374 by AM BV III, 54,502 by BV III GP and 1,369 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein.
(3) The shares were sold as follows: 222 by BBBV, 30 by BV PF, 3 by AM 1999, 13 by BV III, 192 by BV III QP, 16 by BV KG, 6 by BV III PF, 5 by AM BV III and 13 by BV III GP.
(4) The shares are held as follows: 943,285 by BBBV, 127,164 by BV PF, 11,248 by AM 1999, 54,788 by BV III, 814,761 by BV III QP, 68,852 by BV KG, 24,606 by BV III PF, 19,369 by AM BV III, 54,489 by BV III GP and 1,369 by MPM LP. The Reporting Person disclaims beneficial ownership of all such shares except to the extent of his proportionate pecuniary interests therein.
(5) The shares were sold as follows: 44 by BBBV, 6 by BV PF, 1 by AM 1999, 3 by BV III, 38 by BV III QP, 3 by BV KG, 1 by BV III PF, 1 by AM BV III and 3 by BV III GP.
(6) The shares are held as follows: 943,241 by BBBV, 127,158 by BV PF, 11,247 by AM 1999, 54,785 by BV III, 814,723 by BV III QP, 68,849 by BV KG, 24,605 by BV III PF, 19,368 by AM BV III, 54,486 by BV III GP and 1,369 by MPM LP. Each Reporting Person disclaims beneficial ownership of the securities except to the extent of their respective proportionate pecuniary interest therein.
(7) The shares were sold as follows: 44 by BBBV, 6 by BV PF, 1 by AM 1999, 3 by BV III, 38 by BV III QP, 3 by BV KG, 1 by BV III PF, 1 by AM BV III and 3 by BV III GP.
(8) The shares are held as follows: 943,197 by BBBV, 127,152 by BV PF, 11,246 by AM 1999, 54,782 by BV III, 814,685 by BV III QP, 68,846 by BV KG, 24,604 by BV III PF, 19,367 by AM BV III, 54,483 by BV III GP and 1,369 by MPM LP. The Reporting Person disclaims beneficial ownership of all such shares except to the extent of his proportionate pecuniary interests therein.
(9) The shares were sold as follows: 624 by BBBV, 84 by BV PF, 7 by AM 1999, 36 by BV III, 538 by BV III QP, 45 by BV KG, 16 by BV III PF, 13 by AM BV III, 36 by BV III GP and 1 by MPM LP.
(10) The shares are held as follows: 942,573 by BBBV, 127,068 by BV PF, 11,239 by AM 1999, 54,746 by BV III, 814,147 by BV III QP, 68,801 by BV KG, 24,588 by BV III PF, 19,354 by AM BV III, 54,447 by BV III GP and 1,368 by MPM LP. The Reporting Person disclaims beneficial ownership of all such shares except to the extent of his proportionate pecuniary interests therein.

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