180 Life Sciences (NASDAQ: ATNF) today announced its entry into an agreement with Prof. Avi Domb of the Hebrew University, School of Pharmacy, and with Prof. Elyad Davidson, of Hadassah Hospital, to perform a clinical pharmacology (“PK”) study of the uptake of cannabidiol (“CBD”) in a formulation that can be delivered as an oral pill. The PK study will seek to determine how much CBD is taken up into the blood of volunteers. “We believe that the new pill formulation has the potential to dramatically improve the availability and absorption of CBD taken orally as a pill, and plan to facilitate clinical studies to test this,” said Prof. Sir Marc Feldmann, executive co-chairman of 180 Life Sciences. “If successful, we believe that this may significantly expand the use of CBD and derivatives and may permit their use in multiple conditions including, most importantly, pain (a huge unmet need where there are few safe drugs), anxiety and … weight management. Recent human studies have demonstrated that CBD can improve post-operative pain and might decrease opioid consumption, an important goal*. This is an exciting prospect and Prof. Domb’s team has a track record in formulating medications for therapeutic use.”
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About 180 Life Sciences Corp.
180 Life Sciences is a clinical stage biotechnology company focused on the development of therapeutics for unmet medical needs in chronic pain, inflammation and fibrosis by employing innovative research, and, where appropriate, combination therapy. The company’s current primary focus is a novel program to treat several inflammatory disorders using anti-TNF (tumor necrosis factor).
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*Talk by Michael J. Alaia, MD, FAAOS concerning the efficacy of an orally absorbed CBD tablet for postoperative pain relief following rotator cuff surgery. Presented at the 2022 American Academy of Orthopaedic Surgeons Annual Meeting.
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