Global Lipid Nanodiscs Market | Key players are Merck KGaA, Cube Biotech, Anatrace Products, LLC, ideXlab, MEMPRO USA LTD, and NanoTemper.

The Global Lipid Nanodiscs Market is estimated to exhibit a CAGR of 7.9% during the forecast period.

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Large organic molecules known as lipids are categorized as derivatives of fatty acids or closely related substances. Lipids are often soluble in alcohols and organic solvents but not in water. Since it provides a home for resilient membrane proteins, nanodisc technology (NDT) has recently gained popularity as a valuable tool for biochemical and molecular model systems of membrane proteins. They have also been widely used in the isolation, purification, and solubilization of membrane proteins for preparative and analytical procedures. Increasing lipid nanodisc research and development activities and emerging nanodisc production methods for various uses, including the development of drugs and cancer vaccines, are primarily driving the market growth. Moreover, nanodisc technology’s growing advantages for manufacturing pharmaceutical commercial medicines and novel nanodisc engineering advancements like covalently circularized nanodiscs (cND) and DNA corralled nanodiscs are the significant factors contributing to the market revenue growth. Since this product is crucial in treating chronic illnesses like diabetes, cancer, cystic fibrosis, asthma, and arthritis, the market is anticipated to rise dramatically over the coming years.

List of Prominent Players in the Lipid Nanodiscs Market:

Merck KGaA

Cube Biotech

Anatrace Products, LLC

ideXlab

MEMPRO USA LTD

NanoTemper

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Market Dynamics:

Drivers-

Growing scientific interest in phospholipid nanodiscs, which generate a native-like membrane environment and make it easier to prepare physiologically active folded versions of integral membrane proteins, is expected to fuel market revenue growth. The scientific community has paid close attention to these phospho-lipid bilayer nanodiscs as stable and programmable membrane mimics for researching membrane proteins. The growing advantages of Nanodisc technology over conventional integral membrane proteins for the manufacturing of commercial pharmaceutical medicines are another factor that is anticipated to fuel market revenue growth. Membrane proteins are ideal candidates for creating new treatments because they play a critical role in various biological processes, including signal transduction, transport, and enzymes in different metabolic pathways.

Challenges:

Consumers are constraining the development of this industry in developing nations that are not aware of the health advantages of lipids. This is due to the market for lipid nutrition experiencing restrictions due to the availability of substitute products and reduced penetration throughout the perspective period. According to estimates, the following factors would likely slow the expansion of the global market: unsuitability for patients with specific health conditions, high maturity among raw material suppliers, sustainability issues with fishing, and low catch limits. Rising technology and raw materials costs will challenge the lipid market during the hypothetical timeframe.

Regional Trends:

During the forecast period, North America’s revenue is anticipated to expand quickly. The market growth in the area is primarily driven by increased spending on research and development activities, emerging biotechnology startups related to nanodisc platforms, the presence of various research organizations, and partnerships with significant pharmaceutical companies for nanodisc technologies. With the increasing rates of diabetes and obesity, which call for a healthy diet, North America dominates this industry. A rise in the regional market is anticipated as a result of expanding food and beverage production and dietary supplement-friendly legislation.

Recent Developments:

• In February 2022, Merck announced the completion of the transaction to purchase Exelead for approximately USD 780 million in cash, subject to regulatory approvals and other usual closing conditions. Through the company combination, Merck’s Life Science division will be able to provide its clients with comprehensive contract development and manufacturing organization (CDMO) services that span the whole mRNA value chain. Over the next ten years, Merck intends to invest an additional €500 million to scale up Exelead’s technology.
• In March 2022, NanoTemper Technologies announced the availability of Spectral Shift technology in their Dianthus instrument, which was designed to tackle the most difficult affinity-based screenings in drug development. With the help of this ground-breaking method, scientists can now cope with extremely complicated molecular interactions that are frequently present under challenging medications and therapeutic targets, such as fragment libraries, intrinsically disordered proteins (IDPs), and proteolysis-targeting chimaeras (PROTACs).

Segmentation of Lipid Nanodiscs Market-

By Type

• Membrane Scaffold Protein (MSP) Nanodiscs
• Synthetic Nanodiscs

By Application

• Cancer
• Neurodegenerative Diseases
• Infectious disease
• Drug development & discovery
• Others

By Region-

North America-

• The US
• Canada
• Mexico

Europe-

• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe

Asia-Pacific-

• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific

Latin America-

• Brazil
• Argentina
• Rest of Latin America

 Middle East & Africa-

• GCC Countries
• South Africa
• Rest of Middle East and Africa

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